Human aortic aneurysm is commonly characterized by the presence of advanced
atherosclerosis associated with variable chronic adventitial inflammation. Histological
examination of human aortic aneurysmal specimens revealed the presence of plasma cells
and lymphoid aggregates in media and adventitia of the vessels. Immunostaining further
demonstrated that CD3-positive T lymphocytes are present in follicles. Using a highly
sensitive reverse transcription-polymerase chain reaction amplification method, the T cell …