Congo red inhibition of scrapie agent replication
B Caughey, D Ernst, RE Race - Journal of virology, 1993 - Am Soc Microbiol
B Caughey, D Ernst, RE Race
Journal of virology, 1993•Am Soc MicrobiolCongo red inhibits the accumulation of protease-resistant PrP in scrapie-infected mouse
neuroblastoma cells. Here we show that Congo red also inhibits the replication of scrapie
infectivity in these cells. This observation is consistent with the idea that protease-resistant
PrP is a vital component of the scrapie agent or that agent replication depends on the
presence of protease-resistant PrP in the cell.
neuroblastoma cells. Here we show that Congo red also inhibits the replication of scrapie
infectivity in these cells. This observation is consistent with the idea that protease-resistant
PrP is a vital component of the scrapie agent or that agent replication depends on the
presence of protease-resistant PrP in the cell.
Congo red inhibits the accumulation of protease-resistant PrP in scrapie-infected mouse neuroblastoma cells. Here we show that Congo red also inhibits the replication of scrapie infectivity in these cells. This observation is consistent with the idea that protease-resistant PrP is a vital component of the scrapie agent or that agent replication depends on the presence of protease-resistant PrP in the cell.
American Society for Microbiology