[HTML][HTML] Assessment of induction of biliverdin reductase in a mouse model of middle cerebral artery occlusion
N Panahian, MD Maines - Brain Research Protocols, 2000 - Elsevier
Reproducible animal models of stroke are indispensable for investigation of pathogenesis
and treatment of ischemic brain injury. Defined location and size of infarction as well as
consistent production of neurological deficits make it possible to evaluate therapeutic
potential of neuroprotective agents as well as to assess the impact of gene deletion [Nat.
Med. 3 (1997) 1089; Science 265 (1994) 1883; Nat. Med. 4 (1998) 228] or overexpression
[J. Neurochem. 72 (1999) 1187; J. Neurosci. 17 (1997) 7655] on neuroprotection in …
and treatment of ischemic brain injury. Defined location and size of infarction as well as
consistent production of neurological deficits make it possible to evaluate therapeutic
potential of neuroprotective agents as well as to assess the impact of gene deletion [Nat.
Med. 3 (1997) 1089; Science 265 (1994) 1883; Nat. Med. 4 (1998) 228] or overexpression
[J. Neurochem. 72 (1999) 1187; J. Neurosci. 17 (1997) 7655] on neuroprotection in …