Neonatal reversible focal cerebral ischemia: a new model
N Derugin, DM Ferriero, ZS Vexler - Neuroscience research, 1998 - Elsevier
While numerous animal models exist for studying neonatal brain injury after cerebral
ischemia-hypoxia, an adequate model for assessing reversible focal ischemia in the
neonatal rat has not been reported. This paper describes in detail a new surgical procedure
for creating a non-hemorrhagic, reperfused focal ischemic lesion in the neonatal, 7-day-old
rat pup.
ischemia-hypoxia, an adequate model for assessing reversible focal ischemia in the
neonatal rat has not been reported. This paper describes in detail a new surgical procedure
for creating a non-hemorrhagic, reperfused focal ischemic lesion in the neonatal, 7-day-old
rat pup.