[HTML][HTML] Characterization of recombinant human fibroblast growth factor (FGF)-10 reveals functional similarities with keratinocyte growth factor (FGF-7)
M Igarashi, PW Finch, SA Aaronson - Journal of Biological Chemistry, 1998 - ASBMB
A newly identified member of the fibroblast growth factor (FGF) family, designated FGF-10, is
expressed during development and preferentially in adult lung. The predicted FGF-10
protein is most related to keratinocyte growth factor (KGF, or FGF-7). The latter is unique
among FGFs in that it binds and signals only through the FGF receptor (FGFR2b) isoform
KGF receptor (KGFR) expressed specifically by epithelial cells. In order to examine the
biological and biochemical properties of human FGF-10, we isolated the cDNA and …
expressed during development and preferentially in adult lung. The predicted FGF-10
protein is most related to keratinocyte growth factor (KGF, or FGF-7). The latter is unique
among FGFs in that it binds and signals only through the FGF receptor (FGFR2b) isoform
KGF receptor (KGFR) expressed specifically by epithelial cells. In order to examine the
biological and biochemical properties of human FGF-10, we isolated the cDNA and …