The major kidney band 3 gene transcript predicts an amino-terminal truncated band 3 polypeptide

FC Brosius III, SL Alper, AM Garcia… - Journal of Biological …, 1989 - Elsevier
FC Brosius III, SL Alper, AM Garcia, HF Lodish
Journal of Biological Chemistry, 1989Elsevier
We have characterized multiple transcripts from the band 3 gene expressed in rat and
mouse kidney. In each species, the major transcript lacks sequence from the first three
exons of the band 3 gene. The murine transcript predicts a kidney band 3 polypeptide with a
truncated amino terminus, lacking the first 79 amino acids of erythroid band 3. When
expressed in Xenopus oocytes this truncated band 3 functions in anion transport.
We have characterized multiple transcripts from the band 3 gene expressed in rat and mouse kidney. In each species, the major transcript lacks sequence from the first three exons of the band 3 gene. The murine transcript predicts a kidney band 3 polypeptide with a truncated amino terminus, lacking the first 79 amino acids of erythroid band 3. When expressed in Xenopus oocytes this truncated band 3 functions in anion transport.
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