Hereditary pancreatitis: a model for understanding the genetic basis of acute and chronic pancreatitis
DC Whitcomb - Pancreatology, 2001 - Elsevier
Progress in understanding pancreatic diseases has been limited by a number of factors.
Primary problems include the absence of good animal models, and difficulty in
understanding the origin of pancreatic disease since the disease is usually manifest by the
progressive destruction of the gland itself. Beginning in 1995, our laboratory, with the
support of the Midwest Multicenter Pancreatic Study Group, began investigating the genetic
basis of hereditary pancreatitis. Utilization of information becoming available through the …
Primary problems include the absence of good animal models, and difficulty in
understanding the origin of pancreatic disease since the disease is usually manifest by the
progressive destruction of the gland itself. Beginning in 1995, our laboratory, with the
support of the Midwest Multicenter Pancreatic Study Group, began investigating the genetic
basis of hereditary pancreatitis. Utilization of information becoming available through the …