Modulation of neutrophil apoptosis by granulocyte colony-stimulating factor and granulocyte/macrophage colony-stimulating factor during the course of acute …

G Matute-Bello, CW Liles, II Frank Radella… - Critical care …, 2000 - journals.lww.com
Objective: To determine whether bronchoalveolar lavage fluid (BALF) from patients either at
risk for the acute respiratory distress syndrome (ARDS) or with sustained ARDS modulates
neutrophil apoptosis; to measure the BALF concentrations of the apoptosis inhibitors
granulocyte colony-stimulating factor (G-CSF) and granulocyte/macrophage colony-
stimulating factor (GM-CSF) before and after the onset of ARDS; and to determine whether
the BALF concentrations of G-CSF and/or GM-CSF are associated with clinical outcome …