[HTML][HTML] Hepatic apolipoprotein E expression promotes very low density lipoprotein-apolipoprotein B production in vivo in mice
C Maugeais, UJF Tietge, K Tsukamoto, JM Glick… - Journal of Lipid …, 2000 - ASBMB
In addition to its role in the uptake of apolipoprotein B (apoB)-containing lipoproteins, apoE
promotes hepatic very low density lipoprotein-triglyceride (VLDL-TG) production in animal
models. However, it is not known if apoE increases the amount of TG per VLDL particle or
the number of VLDL particles secreted. VLDL-apoB production is a measure of the rate of
VLDL particle secretion. We determined the effects of apoE deficiency and apoE
overexpression on VLDL-apoB production in mice.[35 S] methionine was injected into …
promotes hepatic very low density lipoprotein-triglyceride (VLDL-TG) production in animal
models. However, it is not known if apoE increases the amount of TG per VLDL particle or
the number of VLDL particles secreted. VLDL-apoB production is a measure of the rate of
VLDL particle secretion. We determined the effects of apoE deficiency and apoE
overexpression on VLDL-apoB production in mice.[35 S] methionine was injected into …