The use of animal models to study disease pathogenesis is essential and several animal
models of RA have been used in a wide variety of different studies focusing on problems
such as the identification of the inflammatory mediators in RA, the analysis of genetic factors
associated with susceptibility to RA, and the identification and characterization of markers
suitable for early diagnosis and/or for monitoring the progression of the disease. In this short
review we summarize the unique and distinct features of collagen-induced arthritis (CIA) in …