Asymptomatic Infection with Borrelia burgdorferi

AC Steere, VK Sikand, RT Schoen… - Clinical infectious …, 2003 - academic.oup.com
AC Steere, VK Sikand, RT Schoen, J Nowakowski
Clinical infectious diseases, 2003academic.oup.com
The natural history of asymptomatic seroconversion to Borrelia burgdorferi has been
unclear. We report here, on the basis of a post hoc assessment, the frequency and outcome
of asymptomatic seroconversion to B. burgdorferi in participants of a large Lyme disease
vaccine trial. We show that infection with B. burgdorferi may be asymptomatic but that
asymptomatic infection is unusual in the United States.
The natural history of asymptomatic seroconversion to Borrelia burgdorferi has been unclear. We report here, on the basis of a post hoc assessment, the frequency and outcome of asymptomatic seroconversion to B. burgdorferi in participants of a large Lyme disease vaccine trial. We show that infection with B. burgdorferi may be asymptomatic but that asymptomatic infection is unusual in the United States.
Oxford University Press