Viral burden in genital secretions determines male-to-female sexual transmission of HIV-1: a probabilistic empiric model
H Chakraborty, PK Sen, RW Helms, PL Vernazza… - Aids, 2001 - journals.lww.com
Aids, 2001•journals.lww.com
Objective To develop a model to predict transmission of HIV-1 from men to women. Design
HIV-1 in seminal plasma, and endocervical CCR5 receptors were correlated with
epidemiological studies of HIV-1 transmission to develop a probabilistic model. Settings
Semen samples were collected from patient subjects in Seattle Washington, Chapel Hill,
North Carolina, and St. Gallen, Switzerland. Endocervical biopsy specimens were obtained
from women in Chicago, Illinois.
HIV-1 in seminal plasma, and endocervical CCR5 receptors were correlated with
epidemiological studies of HIV-1 transmission to develop a probabilistic model. Settings
Semen samples were collected from patient subjects in Seattle Washington, Chapel Hill,
North Carolina, and St. Gallen, Switzerland. Endocervical biopsy specimens were obtained
from women in Chicago, Illinois.
Objective To develop a model to predict transmission of HIV-1 from men to women.
Design HIV-1 in seminal plasma, and endocervical CCR5 receptors were correlated with epidemiological studies of HIV-1 transmission to develop a probabilistic model.
Settings Semen samples were collected from patient subjects in Seattle Washington, Chapel Hill, North Carolina, and St. Gallen, Switzerland. Endocervical biopsy specimens were obtained from women in Chicago, Illinois.
Lippincott Williams & Wilkins