Real-time, universal screening for acute HIV infection in a routine HIV counseling and testing population
CD Pilcher, JT McPherson, PA Leone, M Smurzynski… - Jama, 2002 - jamanetwork.com
ContextAcute human immunodeficiency virus (HIV) infection cannot be diagnosed by routine
antibody tests and is rarely diagnosed in clinical practice. However, HIV nucleic acid–based
testing is widely used to screen for antibody-negative acute infection among low-risk blood
donors. ObjectiveTo assess the feasibility of screening in high-volume laboratories for acute
and long-term HIV infection in a routine HIV testing population, in which HIV infection
prevalence is low, using specimen pooling and HIV RNA reverse transcriptase-polymerase …
antibody tests and is rarely diagnosed in clinical practice. However, HIV nucleic acid–based
testing is widely used to screen for antibody-negative acute infection among low-risk blood
donors. ObjectiveTo assess the feasibility of screening in high-volume laboratories for acute
and long-term HIV infection in a routine HIV testing population, in which HIV infection
prevalence is low, using specimen pooling and HIV RNA reverse transcriptase-polymerase …