Maxi-KCa, a Unique Member of the Voltage-Gated K Channel Superfamily
L Toro, M Wallner, P Meera, Y Tanaka - Physiology, 1998 - journals.physiology.org
L Toro, M Wallner, P Meera, Y Tanaka
Physiology, 1998•journals.physiology.orgLarge-conductance, voltage-, and Ca2+-sensitive K+ (maxi-KCa) channels regulate
neuronal and smooth muscle excitability. Their pore-forming α-subunit shows similarities
with voltage-gated channels and indeed can open in the practical absence of Ca2+. The
NH2 terminus is unique, with a seventh transmembrane segment involved in β-subunit
modulation. The long COOH terminus is implied in Ca2+ modulation.
neuronal and smooth muscle excitability. Their pore-forming α-subunit shows similarities
with voltage-gated channels and indeed can open in the practical absence of Ca2+. The
NH2 terminus is unique, with a seventh transmembrane segment involved in β-subunit
modulation. The long COOH terminus is implied in Ca2+ modulation.
Large-conductance, voltage-, and Ca2+-sensitive K+ (maxi-KCa) channels regulate neuronal and smooth muscle excitability. Their pore-forming α-subunit shows similarities with voltage-gated channels and indeed can open in the practical absence of Ca2+. The NH2 terminus is unique, with a seventh transmembrane segment involved in β-subunit modulation. The long COOH terminus is implied in Ca2+ modulation.
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