[HTML][HTML] Disruption of the Saccharomyces cerevisiae homologue to the murine fatty acid transport protein impairs uptake and growth on long-chain fatty acids
NJ Færgeman, CC DiRusso, A Elberger… - Journal of Biological …, 1997 - ASBMB
The yeast Saccharomyces cerevisiae is able to utilize exogenous fatty acids for a variety of
cellular processes including β-oxidation, phospholipid biosynthesis, and protein
modification. The molecular mechanisms that govern the uptake of these compounds in S.
cerevisiae have not been described. We report the characterization of FAT1, a gene that
encodes a putative membrane-bound long-chain fatty acid transport protein (Fat1p). Fat1p
contains 623 amino acid residues that are 33% identical and 54% with similar chemical …
cellular processes including β-oxidation, phospholipid biosynthesis, and protein
modification. The molecular mechanisms that govern the uptake of these compounds in S.
cerevisiae have not been described. We report the characterization of FAT1, a gene that
encodes a putative membrane-bound long-chain fatty acid transport protein (Fat1p). Fat1p
contains 623 amino acid residues that are 33% identical and 54% with similar chemical …