The pathogenesis of the early skin lesion in leprosy.

DS Ridley - Journal of Pathology, 1973 - cabdirect.org
DS Ridley
Journal of Pathology, 1973cabdirect.org
" A study of early skin lesions of leprosy patients, many of them with a history known to be of
less than 1 year's duration, showed that by the use of serial sections the great majority could
be classified on an immunological basis in much the same way as the lesions of established
leprosy. It was also shown that they could be classified according to their predominant
distribution as neural, vascular or subepidermal." Lesions of the vascular type are multiple
and blood disseminated, though they appear to originate in nerves. The subepidermal type …
Abstract
" A study of early skin lesions of leprosy patients, many of them with a history known to be of less than 1 year's duration, showed that by the use of serial sections the great majority could be classified on an immunological basis in much the same way as the lesions of established leprosy. It was also shown that they could be classified according to their predominant distribution as neural, vascular or subepidermal.
" Lesions of the vascular type are multiple and blood disseminated, though they appear to originate in nerves. The subepidermal type are solitary lesions and there is evidence that in many cases transmission is through the epidermis. Intra-epidermal lesions are described. The neural type constitute a mixed group.
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