Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis: a gene microarray analysis
I Nomura, B Gao, M Boguniewicz, MA Darst… - Journal of Allergy and …, 2003 - Elsevier
BACKGROUND: Atopic dermatitis (AD) and psoriasis are the two most common chronic
inflammatory skin diseases. Both of these diseases have distinct clinical findings and
specific inflammatory cell infiltrates. Previous reports have focused individually on one or
two genes or gene products in the lesions of both skin diseases. However, they have not
captured the complex gene expression that must occur to induce specific cellular infiltrates
in the skin lesions of these two diseases. DNA microarray studies allow the simultaneous …
inflammatory skin diseases. Both of these diseases have distinct clinical findings and
specific inflammatory cell infiltrates. Previous reports have focused individually on one or
two genes or gene products in the lesions of both skin diseases. However, they have not
captured the complex gene expression that must occur to induce specific cellular infiltrates
in the skin lesions of these two diseases. DNA microarray studies allow the simultaneous …