[HTML][HTML] The role of nitric oxide and other endothelium-derived vasoactive substances in vascular disease
RA Cohen - Progress in cardiovascular diseases, 1995 - Elsevier
Alteration in the release and action of endothelium-derived vasoactive factors is responsible
for changes in vascular reactivity early in the course of vascular disease. These factors
include nitric oxide, eicosanoids, endothelium-derived hyperpolarizing factor, endothelin,
and angiotensin II. Because endothelial dysfunction occurs at early stages of disease, it may
reflect physiological changes that, if allowed to become chronic, are responsible for changes
in vascular structure and growth and adhesivity to platelets and leukocytes, ultimately …
for changes in vascular reactivity early in the course of vascular disease. These factors
include nitric oxide, eicosanoids, endothelium-derived hyperpolarizing factor, endothelin,
and angiotensin II. Because endothelial dysfunction occurs at early stages of disease, it may
reflect physiological changes that, if allowed to become chronic, are responsible for changes
in vascular structure and growth and adhesivity to platelets and leukocytes, ultimately …