Immunopathology in central nervous system human African trypanosomiasis.
CA Hunter, PGE Kennedy - 1992 - cabidigitallibrary.org
1992•cabidigitallibrary.org
Current knowledge concerning the invasion of the central nervous system and subsequent
damage eventually giving rise to the neurological manifestations of human African
trypanosomiasis (due to Trypanosoma gambiense and T. rhodesiense) is reviewed.
Treatment, proposed mechanisms to account for the neuropathology observed both in man
and a number of animal models, and the role of immune complexes in mediating the
inflammatory processes in the CNS, are discussed.
damage eventually giving rise to the neurological manifestations of human African
trypanosomiasis (due to Trypanosoma gambiense and T. rhodesiense) is reviewed.
Treatment, proposed mechanisms to account for the neuropathology observed both in man
and a number of animal models, and the role of immune complexes in mediating the
inflammatory processes in the CNS, are discussed.
Abstract
Current knowledge concerning the invasion of the central nervous system and subsequent damage eventually giving rise to the neurological manifestations of human African trypanosomiasis (due to Trypanosoma gambiense and T. rhodesiense) is reviewed. Treatment, proposed mechanisms to account for the neuropathology observed both in man and a number of animal models, and the role of immune complexes in mediating the inflammatory processes in the CNS, are discussed.
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