Identification and expression of the gene encoding phosphonopyruvate decarboxylase of Streptomyces hygroscopicus
H Nakashita, K Kozuka, T Hidaka, O Hara… - Biochimica et Biophysica …, 2000 - Elsevier
The first step of C–P compound biosynthesis is a C–P bond formation reaction catalyzed by
phosphoenolpyruvate phosphomutase, but this reaction favors the cleavage of the C–P
bond. This C–P bond forming reaction is driven by the following reaction catalyzed by
phosphonopyruvate (PnPy) decarboxylase. We have cloned and sequenced the gene
(bcpC) encoding PnPy decarboxylase, a key enzyme of C–P compound biosynthesis, from
the bialaphos (BA) producing microorganism Streptomyces hygroscopicus by …
phosphoenolpyruvate phosphomutase, but this reaction favors the cleavage of the C–P
bond. This C–P bond forming reaction is driven by the following reaction catalyzed by
phosphonopyruvate (PnPy) decarboxylase. We have cloned and sequenced the gene
(bcpC) encoding PnPy decarboxylase, a key enzyme of C–P compound biosynthesis, from
the bialaphos (BA) producing microorganism Streptomyces hygroscopicus by …