Molecular biology of the LysR family of transcriptional regulators
MA Schell - Annual review of microbiology, 1993 - annualreviews.org
MA Schell
Annual review of microbiology, 1993•annualreviews.orgMOLECULAR BIOLOGY OF THE LysR FAMILY OF TRANSCRIPTIONAL REGULATORS Page 1
Annu. Rev. Microbiol. 1993. 47:597-{J26 Copyright © 1993 by Annual Reviews Inc. All rights
reserved MOLECULAR BIOLOGY OF THE LysR FAMILY OF TRAi'lSCRIPTIONAL
REGlTLATORS Mark A. Schell Department of Microbiology, University of Georgia, Athens,
Georgia 30602 KEY WORDS: transcription activation, DNA binding, helix-turn-helix, protein
domains CONTENTS INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 598 …
Annu. Rev. Microbiol. 1993. 47:597-{J26 Copyright © 1993 by Annual Reviews Inc. All rights
reserved MOLECULAR BIOLOGY OF THE LysR FAMILY OF TRAi'lSCRIPTIONAL
REGlTLATORS Mark A. Schell Department of Microbiology, University of Georgia, Athens,
Georgia 30602 KEY WORDS: transcription activation, DNA binding, helix-turn-helix, protein
domains CONTENTS INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 598 …
Abstract
The LysR family is composed of> 50 similar-sized, autoregulatory transcrip tional regulators (LTTRs) that apparently evolved from a distant ancestor into subfamilies found in diverse prokaryotic genera. In response to different
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