Ordered structure of the stratum corneum of mammalian skin
JC Mackenzie - Nature, 1969 - nature.com
JC Mackenzie
Nature, 1969•nature.comTHE stratum corneum of mammalian skin usually appears in histological preparations as a
loosely arranged layer of squames with little organization. The absence of organization is
incompatible with the important barrier function of this layer and it has been suggested that
histological processing severely distorts the true structure1. The boundaries of the cells of
the stratum corneum can be clearly seen after treating unfixed sections with sodium
hydroxide solution, because this causes the stratum corneum to swell but leaves the cell …
loosely arranged layer of squames with little organization. The absence of organization is
incompatible with the important barrier function of this layer and it has been suggested that
histological processing severely distorts the true structure1. The boundaries of the cells of
the stratum corneum can be clearly seen after treating unfixed sections with sodium
hydroxide solution, because this causes the stratum corneum to swell but leaves the cell …
Abstract
THE stratum corneum of mammalian skin usually appears in histological preparations as a loosely arranged layer of squames with little organization. The absence of organization is incompatible with the important barrier function of this layer and it has been suggested that histological processing severely distorts the true structure1. The boundaries of the cells of the stratum corneum can be clearly seen after treating unfixed sections with sodium hydroxide solution, because this causes the stratum corneum to swell but leaves the cell membranes of this layer intact2,3.
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