[HTML][HTML] An Alternative Splicing Product of the Lamin A/C Gene Lacks Exon 10 (∗)
BM Machiels, AHG Zorenc, JM Endert… - Journal of biological …, 1996 - ASBMB
Expression of the A-type lamins was studied in the lung adenocarcinoma cell line GLC-A1. A-
type lamins, consisting of lamin A and C, are two products arising from the same gene by
alternative splicing. Northern blotting showed in GLC-A1 a relatively low expression level of
lamin C and an even lower expression level of lamin A as compared to other
adenocarcinoma cell lines. Immunofluorescence studies revealed highly irregular nuclear
inclusions of lamin A, suggesting protein or gene expression abnormalities. Reverse …
type lamins, consisting of lamin A and C, are two products arising from the same gene by
alternative splicing. Northern blotting showed in GLC-A1 a relatively low expression level of
lamin C and an even lower expression level of lamin A as compared to other
adenocarcinoma cell lines. Immunofluorescence studies revealed highly irregular nuclear
inclusions of lamin A, suggesting protein or gene expression abnormalities. Reverse …