Hyperhomocysteinemia: a risk factor for placental abruption or infarction

TAW Goddijn-Wessel, MGAJ Wouters… - European Journal of …, 1996 - Elsevier
Objective: To establish the prevalence of hyperhomocysteinemia in women with placental
abruption or infarction. Design: Forty-six women with normal pregnancy outcome (controls)
and 84 women with placental abruption or infarction (study group) were selected, and
studied in the non-pregnant state. Homocysteine metabolism was investigated by a
standardized oral methionine loading test. Hyperhomocysteinemia was defined as a
concentration of fasting and/or postmethionine plasma homocysteine exceeding the …