Protection against oral and gastrointestinal diseases: importance of dietary nitrate intake, oral nitrate reduction and enterosalivary nitrate circulation
C Duncan, H Li, R Dykhuizen, R Frazer… - … and Physiology Part A …, 1997 - Elsevier
Over the last 20 years, dietary nitrate has been implicated in the formation of methemoglobin
and carcinogenic nitrosamines in humans. This has led to restrictions of nitrate and nitrite
levels in food and drinking water. However, there is no epidemiological evidence for an
increased risk of gastric and intestinal cancer in population groups with high dietary
vegetable or nitrate intake. A reevaluation of our currently very negative perception of dietary
nitrates comes from recent research into the metabolism and enterosalivary circulation of …
and carcinogenic nitrosamines in humans. This has led to restrictions of nitrate and nitrite
levels in food and drinking water. However, there is no epidemiological evidence for an
increased risk of gastric and intestinal cancer in population groups with high dietary
vegetable or nitrate intake. A reevaluation of our currently very negative perception of dietary
nitrates comes from recent research into the metabolism and enterosalivary circulation of …