Purinergic receptor signaling at the basolateral membrane of macula densa cells
R Liu, PD Bell, J Peti-Peterdi, G Kovacs… - Journal of the …, 2002 - journals.lww.com
Purinergic receptors are important in the regulation of renal hemodynamics; therefore, this
study sought to determine if such receptors influence macula densa cell function. Isolated
glomeruli containing macula densa cells, with and without the cortical thick ascending limb,
were loaded with the Ca 2+ sensitive indicators, Fura Red (confocal microscopy) or fura 2
(conventional video image analysis). Studies were performed on an inverted microscope in
a chamber with a flow-through perfusion system. Changes in cytosolic calcium concentration …
study sought to determine if such receptors influence macula densa cell function. Isolated
glomeruli containing macula densa cells, with and without the cortical thick ascending limb,
were loaded with the Ca 2+ sensitive indicators, Fura Red (confocal microscopy) or fura 2
(conventional video image analysis). Studies were performed on an inverted microscope in
a chamber with a flow-through perfusion system. Changes in cytosolic calcium concentration …