A study on the density and distribution of uterine Natural Killer cells at mid pregnancy in mice genetically-ablated for CCR2, CCR 5 and the CCR5 receptor ligand, MIP …
S Chantakru, WA Kuziel, N Maeda, BA Croy - Journal of reproductive …, 2001 - Elsevier
Several chemoattractants mediate Natural Killer (NK) cell migration. The CC-chemokines,
monocyte inflammatory protein (MIP)-1α, regulated upon activation, normal T cell expressed
and secreted (RANTES) and macrophage chemotactic protein (MCP)-1 are the most potent.
Peripheral NK cells express the CC-chemokine receptor CCR2, for MCP-1 and CCR5, for
MIP-1α and RANTES. These chemokines are detected in the uterus during the estrous cycle
and become elevated during pregnancy. To assess the roles of CCR2, CCR5 and MIP-1α in …
monocyte inflammatory protein (MIP)-1α, regulated upon activation, normal T cell expressed
and secreted (RANTES) and macrophage chemotactic protein (MCP)-1 are the most potent.
Peripheral NK cells express the CC-chemokine receptor CCR2, for MCP-1 and CCR5, for
MIP-1α and RANTES. These chemokines are detected in the uterus during the estrous cycle
and become elevated during pregnancy. To assess the roles of CCR2, CCR5 and MIP-1α in …