[HTML][HTML] Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin …

I Kim, SO Moon, SH Kim, HJ Kim, YS Koh… - Journal of Biological …, 2001 - ASBMB
Vascular endothelial growth factor (VEGF) induces adhesion molecules on endothelial cells
during inflammation. Here we examined the mechanisms underlying VEGF-stimulated
expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1
(VCAM-1), and E-selectin in human umbilical vein endothelial cells. VEGF (20 ng/ml)
increased expression of ICAM-1, VCAM-1, and E-selectin mRNAs in a time-dependent
manner. These effects were significantly suppressed by Flk-1/kinase-insert domain …