Estrogens reduce bone loss in the ovariectomized, lactating rat model
SC Garner, JJB Anderson, MH Mar, I Parikh - Bone and mineral, 1991 - Elsevier
Estrogen treatment of ovariectomized, lactating rats improved retention of bone mineral
mass by 15–25% compared to ovariectomized, lactating rats receiving vehicle only. On the
second day postpartum all lactating rats were ovariectomized and were placed along with
age-matched non-mated controls on a whole-wheat flour-based diet with 0.1% calcium and
0.4% phosphorus. On day 6 postpartum estrogen treatment was begun with either
implantation of a slow-release 17β-estradiol pellet or with the first of daily subcutaneous …
mass by 15–25% compared to ovariectomized, lactating rats receiving vehicle only. On the
second day postpartum all lactating rats were ovariectomized and were placed along with
age-matched non-mated controls on a whole-wheat flour-based diet with 0.1% calcium and
0.4% phosphorus. On day 6 postpartum estrogen treatment was begun with either
implantation of a slow-release 17β-estradiol pellet or with the first of daily subcutaneous …