Expression of stem cell factor and its receptor, c-kit, during liver regeneration from putative stem cells in adult rat.
K Fujio, RP Evarts, Z Hu, ER Marsden… - … ; a journal of technical …, 1994 - europepmc.org
K Fujio, RP Evarts, Z Hu, ER Marsden, SS Thorgeirsson
Laboratory investigation; a journal of technical methods and pathology, 1994•europepmc.orgBackground Stem cell factor (SCF) and its receptor, c-kit, are known to play important roles
in hematopoiesis, melanogenesis, and gametogenesis. The biologic effects of the SCF/c-kit
system are believed to involve survival, proliferation, and migration of early stem cell
progeny. Although SCF and c-kit receptor are widely expressed during normal embryonic
development, their expression in the adult is limited.
in hematopoiesis, melanogenesis, and gametogenesis. The biologic effects of the SCF/c-kit
system are believed to involve survival, proliferation, and migration of early stem cell
progeny. Although SCF and c-kit receptor are widely expressed during normal embryonic
development, their expression in the adult is limited.
Background
Stem cell factor (SCF) and its receptor, c-kit, are known to play important roles in hematopoiesis, melanogenesis, and gametogenesis. The biologic effects of the SCF/c-kit system are believed to involve survival, proliferation, and migration of early stem cell progeny. Although SCF and c-kit receptor are widely expressed during normal embryonic development, their expression in the adult is limited.
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