[HTML][HTML] Two murine homologs of the Drosophila single-minded protein that interact with the mouse aryl hydrocarbon receptor nuclear translocator protein

MR Probst, CM Fan, M Tessier-Lavigne… - Journal of Biological …, 1997 - ASBMB
Drosophila single-minded, which acts as a positive master gene regulator in central nervous
system midline formation in Drosophila, its two mouse homologs SIM1 and SIM2, and the
mammalian aryl hydrocarbon receptor (AHR) and aryl hydrocarbon receptor nuclear
translocator (ARNT) proteins are members of the basic-helix-loop-helix· PAS family of
transcription factors. In the yeast two-hybrid system, we demonstrate strong constitutive
interaction of ARNT with SIM1 and SIM2 and fully ligand-dependent interaction of ARNT with …