Publisher Summary The tetracycline (Tc) responsive regulatory systems have been applied
to control gene activities in eukaryotes. They are shown to function in cultured cells from
mammals, plants, amphibians, and insects as well as in whole organisms including yeast,
Drosophila, plants, mice, and rats. The basic regulatory circuits of the Tet systems and the
elements constituting these circuits are based on simple principles. A number of parameters
must be reconciled when setting up one of the systems for a particular purpose. When …