Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb
T Zigova, V Pencea, SJ Wiegand, MB Luskin - Molecular and Cellular …, 1998 - Elsevier
We have previously demonstrated that the most rostral part of the subventricular zone (SVZ)
is a source of neuronal progenitor cells whose progeny are destined to become
interneurons of the olfactory bulb. To determine whether the number of newly generated
neurons in the adult olfactory bulb could be increased by the administration of an
exogenous factor, brain-derived neurotrophic factor (BDNF) was infused for 12 days into the
right lateral ventricle of adult rat brains. The production of new cells was monitored by either …
is a source of neuronal progenitor cells whose progeny are destined to become
interneurons of the olfactory bulb. To determine whether the number of newly generated
neurons in the adult olfactory bulb could be increased by the administration of an
exogenous factor, brain-derived neurotrophic factor (BDNF) was infused for 12 days into the
right lateral ventricle of adult rat brains. The production of new cells was monitored by either …