Functional skewing of bone marrow-derived dendritic cells by Th1-or Th2-inducing cytokines
M Sato, K Iwakabe, S Kimura, T Nishimura - Immunology letters, 1999 - Elsevier
To investigate the functional difference of bone marrow (BM)-derived dendritic cells (DC),
BM cells were cultured under three different cytokine conditions and the induced DC were
temporarily designated as DC0, DC1, or DC2 cells. DC0 were induced by culture of BM cells
with granulocyte–macrophage colony-stimulating factor (GMCSF) plus interleukin 3 (IL-3).
DC1 were induced by culture with Th1-inducing cytokine (IL-12, gamma-interferon—IFN-γ)
in addition to GMCSF plus IL-3. DC2 were induced by culture with Th2-inducing cytokine (IL …
BM cells were cultured under three different cytokine conditions and the induced DC were
temporarily designated as DC0, DC1, or DC2 cells. DC0 were induced by culture of BM cells
with granulocyte–macrophage colony-stimulating factor (GMCSF) plus interleukin 3 (IL-3).
DC1 were induced by culture with Th1-inducing cytokine (IL-12, gamma-interferon—IFN-γ)
in addition to GMCSF plus IL-3. DC2 were induced by culture with Th2-inducing cytokine (IL …