[HTML][HTML] Differential L-selectin binding activities of human hematopoietic cell L-selectin ligands, HCELL and PSGL-1
CJ Dimitroff, JY Lee, KS Schor, BM Sandmaier… - Journal of Biological …, 2001 - ASBMB
Expression of L-selectin on human hematopoietic cells (HC) is associated with a higher
proliferative activity and a more rapid engraftment after hematopoietic stem cell
transplantation. Two L-selectin ligands are expressed on human HCs, P-selectin
glycoprotein ligand-1 (PSGL-1) and a specialized glycoform of CD44 (hematopoietic cell E-
and L-selectin ligand, HCELL). Although the structural biochemistry of HCELL and PSGL-1
is well characterized, the relative capacity of these molecules to mediate L-selectin …
proliferative activity and a more rapid engraftment after hematopoietic stem cell
transplantation. Two L-selectin ligands are expressed on human HCs, P-selectin
glycoprotein ligand-1 (PSGL-1) and a specialized glycoform of CD44 (hematopoietic cell E-
and L-selectin ligand, HCELL). Although the structural biochemistry of HCELL and PSGL-1
is well characterized, the relative capacity of these molecules to mediate L-selectin …