The synovial prostaglandin system in chronic inflammatory arthritis: differential effects of steroidal and nonsteroidal anti-inflammatory drugs
S Bombardieri, P Cattani, G Ciabattoni… - British journal of …, 1981 - ncbi.nlm.nih.gov
S Bombardieri, P Cattani, G Ciabattoni, O Di Munno, G Pasero, C Patrono, E Pinca…
British journal of pharmacology, 1981•ncbi.nlm.nih.govAbstract 1 The present study was undertaken to characterize the spectrum of arachidonic
acid metabolites present in synovial effusions of patients with rheumatoid or psoriatic
arthritis, and to compare changes in their concentration following a short-term treatment with
6α-methyl-prednisolone (6-MeP: 4-8 mg/day) or indoprofen (1.2 g/day), a nonsteroidal anti-
inflammatory agent with proven synovial prostaglandin inhibitory effect.
acid metabolites present in synovial effusions of patients with rheumatoid or psoriatic
arthritis, and to compare changes in their concentration following a short-term treatment with
6α-methyl-prednisolone (6-MeP: 4-8 mg/day) or indoprofen (1.2 g/day), a nonsteroidal anti-
inflammatory agent with proven synovial prostaglandin inhibitory effect.
Abstract
1 The present study was undertaken to characterize the spectrum of arachidonic acid metabolites present in synovial effusions of patients with rheumatoid or psoriatic arthritis, and to compare changes in their concentration following a short-term treatment with 6α-methyl-prednisolone (6-MeP: 4-8 mg/day) or indoprofen (1.2 g/day), a nonsteroidal anti-inflammatory agent with proven synovial prostaglandin inhibitory effect.
ncbi.nlm.nih.gov