Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro.

FA Fitzpatrick, MA Wynalda - The Journal of biological chemistry, 1983 - europepmc.org
FA Fitzpatrick, MA Wynalda
The Journal of biological chemistry, 1983europepmc.org
Human albumin catalyzed the in vitro transformation of prostaglandin D2 into three novel
dehydration products identified as 9-deoxy-11-keto-15 alpha-hydroxy-delta-5, 9, 12-
prostenoic acid; 15-deoxy-11-keto-9 alpha-hydroxy-delta 5, 9, 12, 14-prostenoic acid.
Results suggest that albumin can influence, qualitatively and quantitatively, the metabolism
of eicosanoids.
Human albumin catalyzed the in vitro transformation of prostaglandin D2 into three novel dehydration products identified as 9-deoxy-11-keto-15 alpha-hydroxy-delta-5, 9, 12-prostenoic acid; 15-deoxy-11-keto-9 alpha-hydroxy-delta 5, 9, 12, 14-prostenoic acid. Results suggest that albumin can influence, qualitatively and quantitatively, the metabolism of eicosanoids.
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