[PDF][PDF] Parathyroid hormone‐mediated regulation of renal phosphate reabsorption

J Biber, N Hernando, M Traebert, H Völkl… - Nephrology Dialysis …, 2000 - researchgate.net
Under normal physiological conditions, up to 80% of filtered inorganic phosphate (Pi) is
reabsorbed in prox-To date, molecular details of the signalling cascade imal tubules. Among
the Na-coupled Pi co-transporters leading to an internalization of type IIa co-transporters
identified so far [1], the type IIa Na/Pi co-transporter are not known. Yet, it seems that
activation of protein represents the major player, as it has been shown that kinase A (PKA)
and/or C activity is important. Type I after knocking out the type IIa co-transporter, Na/Pi PTH …