Reexamination of the blood lymphocyte transformation test in the diagnosis of chronic beryllium disease
MM Mroz, K Kreiss, DC Lezotte, PA Campbell… - Journal of allergy and …, 1991 - Elsevier
The T cell response to beryllium, measured in bronchoalveolar lavage by the lymphocyte
transformation test (LTT), is a critical diagnostic test for discriminating between chronic
beryllium disease (CBD) and other granulomatous diseases. We examined the sensitivity,
reproducibility, and methods of a less invasive, peripheral blood LTT in 17 patients with CBD
and in 18 beryllium-exposed control subjects. Ninety-four percent of CBD cases (16 17) had
abnormal blood LTT results, and all 18 beryllium-exposed control subjects had normal blood …
transformation test (LTT), is a critical diagnostic test for discriminating between chronic
beryllium disease (CBD) and other granulomatous diseases. We examined the sensitivity,
reproducibility, and methods of a less invasive, peripheral blood LTT in 17 patients with CBD
and in 18 beryllium-exposed control subjects. Ninety-four percent of CBD cases (16 17) had
abnormal blood LTT results, and all 18 beryllium-exposed control subjects had normal blood …