Targeted gene replacement
MR Capecchi - Scientific American, 1994 - JSTOR
MR Capecchi
Scientific American, 1994•JSTORSuch altered cells are helping researchers to produce mice carrying speci 'c genetic
mutations. The 'nding of a curled tail and a balance-and-hearing disorder in one such
mouse (above) led to the discovery that the a” ected gene, int-2, participates in development
of the tail and the inner ear.
mutations. The 'nding of a curled tail and a balance-and-hearing disorder in one such
mouse (above) led to the discovery that the a” ected gene, int-2, participates in development
of the tail and the inner ear.
Such altered cells are helping researchers to produce mice carrying speci ‘c genetic mutations. The ‘nding of a curled tail and a balance-and-hearing disorder in one such mouse (above) led to the discovery that the a” ected gene, int-2, participates in development of the tail and the inner ear.
JSTOR