A novel peptide nucleic acid monomer for recognition of thymine in triple-helix structures
AB Eldrup, O Dahl, PE Nielsen - Journal of the American Chemical …, 1997 - ACS Publications
AB Eldrup, O Dahl, PE Nielsen
Journal of the American Chemical Society, 1997•ACS PublicationsTriplex targeting of double-stranded DNA using natural nucleobases as introduced ten years
ago1 is still essentially limited to homopurine stretches. The problem lies in the asymmetric
nature of the triple-helix structure, in which only the purine part of the base pair is recognized
by T ‚AT, C+
ago1 is still essentially limited to homopurine stretches. The problem lies in the asymmetric
nature of the triple-helix structure, in which only the purine part of the base pair is recognized
by T ‚AT, C+
Triplex targeting of double-stranded DNA using natural nucleobases as introduced ten years ago1 is still essentially limited to homopurine stretches. The problem lies in the asymmetric nature of the triple-helix structure, in which only the purine part of the base pair is recognized by T ‚AT, C+
ACS Publications