• The phenomenon of calciphylaxis as defined by Selye is a condition of hypersensitivity that
results in acute local calcification of various organs, with a whole host of morbid processes.
Nephrocalcinosis and cutaneous calcifications have long been recognized in patients with
chronic renal failure, but they have not often been reported in actute hyperparathyroidism or
other causes of calcium-phosphate metabolism aberrations. The pathogenesis is not clear,
and both the sensitizer and challenging agent in the hypersensitivity theory are often …