The size of the hepatitis delta agent

LF He, E Ford, RH Purcell, WT London… - Journal of medical …, 1989 - Wiley Online Library
LF He, E Ford, RH Purcell, WT London, J Phillips, JL Gerin
Journal of medical virology, 1989Wiley Online Library
The size of the hepatitis delta virus was determined by filtration of infectious plasma through
polycarbonate membranes and the inoculation of filtrates into chimpanzees. Chimpanzees
inoculated with filtrates of 50 nm and 30 nm, but not 15 nm filters, developed delta hepatitis.
The minimum size of infectious hepatitis delta virus was estimated to be approximately 30
nm, which is consistent with measurements of particles thought to be the virus.
Abstract
The size of the hepatitis delta virus was determined by filtration of infectious plasma through polycarbonate membranes and the inoculation of filtrates into chimpanzees. Chimpanzees inoculated with filtrates of 50 nm and 30 nm, but not 15 nm filters, developed delta hepatitis. The minimum size of infectious hepatitis delta virus was estimated to be approximately 30 nm, which is consistent with measurements of particles thought to be the virus.
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