Reduction of bacterial titers by low-dose aspirin in experimental aortic valve endocarditis
DP Nicolau, CD Freeman, CH Nightingale… - Infection and …, 1993 - Am Soc Microbiol
DP Nicolau, CD Freeman, CH Nightingale, R Quintiliani, CJ Coe, EG Maderazo, BW Cooper
Infection and immunity, 1993•Am Soc MicrobiolUsing a rabbit model of Staphylococcus aureus endocarditis, we studied the effects of
aspirin on the natural progression of this infection. Compared with untreated animals, the
aspirin-treated animals showed a 30%(P= 0.11) reduction in the weight of the vegetations
and an 84%(P= 0.03) reduction in the bacterial titer of the vegetations.
aspirin on the natural progression of this infection. Compared with untreated animals, the
aspirin-treated animals showed a 30%(P= 0.11) reduction in the weight of the vegetations
and an 84%(P= 0.03) reduction in the bacterial titer of the vegetations.
Using a rabbit model of Staphylococcus aureus endocarditis, we studied the effects of aspirin on the natural progression of this infection. Compared with untreated animals, the aspirin-treated animals showed a 30% (P = 0.11) reduction in the weight of the vegetations and an 84% (P = 0.03) reduction in the bacterial titer of the vegetations.
American Society for Microbiology