Effects of systemic interferon-α (IFN-α) on the antigenic phenotype of melanoma metastases. EORTC melanoma group cooperative study No. 18852

U Von Stamm, EB Bröcker… - Melanoma …, 1993 - journals.lww.com
In order to Investigate the effects of in vivo treatment with Intarferon-[alpha](IFM-[alpha]) on
melanoma antigens, a clinical EORTC trial (No. 18852) was accompanied by an
Immunohistological study. Twenty patients with melanoma metastoses of skin and soft
tissues, eventually also of the lung, who were treated with systemic IFN-[alpha], were
evaluated for a comparison of metastases before (40) and during (42) treatment
Representative cryostal sections were studied Immunohistologically with a panel of …