Microscopic visualization of the retina by angiography with high-molecular-weight fluorescein-labeled dextrans in the mouse
Methods currently available for the examination of the retinal vasculature of laboratory
animals have significant drawbacks. Fluorescein angiography of rodent eyes is hampered
by a poor view of the peripheral retina and difficulty in performing fundus photography.
Methods of staining or filling retinal vessels are unreliable, labor-intensive, or have high
backgrounds. We have developed a novel technique that is quick, simple, and accurate.
Fluorescein-labeled 2 million molecular weight dextrans are used to fill the retinal …
animals have significant drawbacks. Fluorescein angiography of rodent eyes is hampered
by a poor view of the peripheral retina and difficulty in performing fundus photography.
Methods of staining or filling retinal vessels are unreliable, labor-intensive, or have high
backgrounds. We have developed a novel technique that is quick, simple, and accurate.
Fluorescein-labeled 2 million molecular weight dextrans are used to fill the retinal …