Bone-marrow transplantation in a patient with the Wiskott-Aldrich syndrome
FH Bach, RJ Albertini, P Joo, JL Anderson, MM Bortin - The Lancet, 1968 - Elsevier
FH Bach, RJ Albertini, P Joo, JL Anderson, MM Bortin
The Lancet, 1968•ElsevierA 2-year-old boy with the Wiskott-Aldrich syndrome has been treated by bone-marrow
transplantation. An initial attempt to transplantation without extensive preparation of the
recipient failed. Subsequently the recipient was prepared with a 4-day course of
cyclophosphamide followed by bone-marrow transplantation from a sister identical at HL-A—
the major histocompatibility locus in man. 6 weeks after transplantation the patient is
chimaric and has shown no evidence of graft-versus-host disease.
transplantation. An initial attempt to transplantation without extensive preparation of the
recipient failed. Subsequently the recipient was prepared with a 4-day course of
cyclophosphamide followed by bone-marrow transplantation from a sister identical at HL-A—
the major histocompatibility locus in man. 6 weeks after transplantation the patient is
chimaric and has shown no evidence of graft-versus-host disease.
Abstract
A 2-year-old boy with the Wiskott-Aldrich syndrome has been treated by bone-marrow transplantation. An initial attempt to transplantation without extensive preparation of the recipient failed. Subsequently the recipient was prepared with a 4-day course of cyclophosphamide followed by bone-marrow transplantation from a sister identical at HL-A— the major histocompatibility locus in man. 6 weeks after transplantation the patient is chimaric and has shown no evidence of graft-versus-host disease.
Elsevier