Specific psychiatric disorders are characterized by impaired selective inhibition or “gating” of
responses to sensory or cognitive information. Less is known about gating differences
among normal individuals. We tested carefully screened controls in measures of central
inhibition: prepulse inhibition (PPI) of startle, the Stroop test, and negative priming (NP).
Subjects were defined as “normal” or “psychosis prone,” based on theoretically and
empirically derived MMPI criteria. Performance on all measures by “psychosis-prone” …