Cortical dysfunction in schizophrenia during auditory word and tone working memory demonstrated by functional magnetic resonance imaging

AA Stevens, PS Goldman-Rakic, JC Gore… - Archives of general …, 1998 - jamanetwork.com
Background Verbal learning and memory deficits are among the most severe cognitive
deficits observed in schizophrenia. We have demonstrated that such deficits do not extend to
working memory for tones in a substantial number of patients even when verbal working
memory is impaired. In this study we used functional magnetic resonance imaging to study
the neural basis of this dissociation of auditory verbal and nonverbal working memory in
individuals with schizophrenia. Methods While undergoing functional magnetic resonance …