Imaging of the apparent diffusion coefficient for the evaluation of cerebral metabolic recovery after cardiac arrest

M Fischer, K Bockhorst, M Hoehn-Berlage… - Magnetic resonance …, 1995 - Elsevier
The apparent diffusion coefficient (ADC) of water is a sensitive indicator of water and ion
homeostasis of brain. Resuscitation of the brain after cardiac arrest, the most frequent
reason for global cerebral ischemia under clinical conditions, depends critically on the
reversal of disturbances of water and ion homeostasis. We, therefore, investigated whether
ADC imaging can be used to monitor the development and reversal of ischemic brain injury
during and after cardiac arrest. Ten adult mongrel normothermic cats were anesthetized with …